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These include (1) the population, intervention, comparison, and outcome (PICO) questions the committee developed for the systematic review; (2) a review of the grading systems used; (3) the species in the complex; (4) examples of hand hygiene opportunities for healthcare personnel, people with CF, and their families; (5) indications for use of personal protective equipment by healthcare personnel, people with CF, and their families; (6) strategies to enhance the effectiveness of environmental cleaning in healthcare settings; (7) strategies for CF clinics to minimize risk of transmission of potential pathogens; (8) strategies to minimize the adverse psychosocial impact of isolation precautions; (9) knowledge, attitudes, and practice barriers related to implementing IP&C in CF; and (10) strategies to enhance implementation of IP&C in CF.
The recommendations highlight the importance of partnering with local IP&C teams to facilitate implementation and the use of existing audit and feedback tools to monitor adherence to IP&C practices.
A draft of the guideline was made available to the CF and IP&C communities for review, and all comments were considered by the committee.
This guideline was reviewed and endorsed by SHEA and by the Association for Professionals in Infection Control (APIC).) are provided with each recommendation.
In this section, as in the 2003 Infection Control Guideline for CF, it is again emphasized that the source of CF pathogens is often unknown and that many individuals with CF are infected with unique strains.
However, molecular epidemiology tools have expanded the evidence that people with CF can share epidemic strains of spp.) are also considered.
During the past decade, new evidence has led to a renewed emphasis on source containment of potential pathogens and the role played by the contaminated healthcare environment in the transmission of infectious agents.